| Houston Texans (7-1) | at | Chicago Bears (7-1) | [-1] | SUN 8 | |
| Detroit Lions (4-4) | at | Minnesota Vikings (5-4) | [-0] | SUN 1 | |
| Atlanta Falcons (8-0) | [-6] | at | New Orleans Saints (3-5) | SUN 1 | |
| San Diego Chargers (4-4) | at | Tampa Bay Buccaneers (4-4) | [-1] | SUN 1 | |
| Oakland Raiders (3-5) | at | Baltimore Ravens (6-2) | [-5] | SUN 1 | |
| New York Jets (3-5) | at | Seattle Seahawks (5-4) | [-3] | SUN 4 | |
| New York Giants (6-3) | [-6] | at | Cincinnati Bengals (3-5) | SUN 1 | |
| Dallas Cowboys (3-5) | [-1] | at | Philadelphia Eagles (3-5) | SUN 4 | |
| St. Louis Rams (3-5) | at | San Francisco 49ers (6-2) | [-8] | SUN 4 | |
| Denver Broncos (5-3) | [-6] | at | Carolina Panthers (2-6) | SUN 1 | |
| Indianapolis Colts (5-3) | [-4] | at | Jacksonville Jaguars (1-7) | THU 8 | |
| Buffalo Bills (3-5) | at | New England Patriots (5-3) | [-10] | SUN 1 | |
| Tennessee Titans (3-6) | at | Miami Dolphins (4-4) | [-9] | SUN 1 | |
| Kansas City Chiefs (1-7) | at | Pittsburgh Steelers (5-3) | [-8] | MON 8 |
Wednesday, November 7, 2012
2012 Week 10 - Game of the Week
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