| Name (* = Rookie) | Team | G | Comp | Att | PassYds | PassTD | Int | RushYds | RushTD | MVP Score | Adj Score |
| Josh Allen | BUF | 3 | 94 | 132 | 1014 | 9 | 2 | 113 | 1 | 342 | 369 |
| Tua Tagovailoa | MIA | 3 | 72 | 101 | 925 | 8 | 2 | 1 | 0 | 267 | 327 |
| Jalen Hurts | PHI | 3 | 65 | 97 | 906 | 4 | 1 | 170 | 3 | 265 | 325 |
| Lamar Jackson | BAL | 3 | 56 | 88 | 749 | 10 | 2 | 243 | 2 | 279 | 301 |
| Patrick Mahomes | KC | 3 | 74 | 109 | 857 | 8 | 1 | 30 | 0 | 271 | 293 |
| Trevor Lawrence | JAX | 3 | 77 | 111 | 772 | 6 | 1 | 22 | 0 | 249 | 269 |
| Justin Herbert | LAC | 3 | 84 | 127 | 910 | 7 | 2 | 9 | 0 | 266 | 243 |
| Carson Wentz | WAS | 3 | 82 | 130 | 861 | 7 | 2 | 57 | 0 | 257 | 235 |
| Geno Smith | SEA | 3 | 79 | 102 | 718 | 4 | 0 | 15 | 0 | 248 | 226 |
| Aaron Rodgers | GB | 3 | 68 | 94 | 684 | 4 | 1 | 8 | 0 | 209 | 226 |
| Kyler Murray | ARI | 3 | 90 | 141 | 784 | 3 | 1 | 65 | 1 | 243 | 222 |
| Kirk Cousins | MIN | 3 | 74 | 119 | 758 | 5 | 3 | 19 | 0 | 200 | 216 |
| Joe Flacco | NYJ | 3 | 91 | 155 | 899 | 5 | 3 | 6 | 0 | 228 | 208 |
| Joe Burrow | CIN | 3 | 80 | 125 | 812 | 6 | 4 | 73 | 0 | 223 | 204 |
| Jared Goff | DET | 3 | 66 | 112 | 748 | 7 | 1 | 17 | 0 | 222 | 203 |
| Jacoby Brissett | CLE | 3 | 61 | 92 | 596 | 4 | 1 | 64 | 0 | 187 | 202 |
| Matthew Stafford | LAR | 3 | 74 | 102 | 761 | 4 | 5 | 4 | 0 | 186 | 201 |
| Tom Brady | TB | 3 | 67 | 103 | 673 | 3 | 1 | -4 | 0 | 184 | 199 |
| Russell Wilson | DEN | 3 | 63 | 106 | 743 | 2 | 0 | 22 | 0 | 179 | 193 |
| Jameis Winston | NO | 3 | 73 | 115 | 858 | 4 | 2 | 16 | 0 | 211 | 193 |
| Daniel Jones | NYG | 3 | 59 | 92 | 560 | 3 | 2 | 125 | 0 | 163 | 176 |
| Matt Ryan | IND | 3 | 75 | 117 | 769 | 3 | 4 | 16 | 0 | 176 | 176 |
| Marcus Mariota | ATL | 3 | 50 | 79 | 640 | 3 | 2 | 92 | 2 | 174 | 159 |
| Mitchell Trubisky | PIT | 3 | 62 | 103 | 569 | 2 | 1 | 23 | 1 | 162 | 148 |
| Cooper Rush | DAL | 3 | 47 | 75 | 514 | 2 | 0 | 0 | 0 | 137 | 148 |
| Derek Carr | LV | 3 | 73 | 120 | 850 | 6 | 4 | 26 | 0 | 206 | 146 |
| Mac Jones | NE | 3 | 64 | 97 | 786 | 2 | 5 | 37 | 1 | 157 | 143 |
| Ryan Tannehill | TEN | 3 | 50 | 80 | 647 | 3 | 3 | 11 | 1 | 145 | 132 |
| Davis Mills | HOU | 3 | 62 | 107 | 662 | 3 | 2 | 0 | 0 | 155 | 127 |
| Baker Mayfield | CAR | 3 | 42 | 81 | 550 | 3 | 1 | 40 | 1 | 134 | 122 |
| Jimmy Garoppolo | SF | 2 | 31 | 50 | 365 | 2 | 1 | 5 | 1 | 100 | 91 |
| Justin Fields | CHI | 3 | 23 | 45 | 297 | 2 | 2 | 95 | 1 | 73 | 79 |
| Name (* = Rookie) | Team | G | Rush | RushYds | RushTD | Rec | RecYds | RecTD | MVP Score | Adj Score |
| Nick Chubb | CLE | 3 | 62 | 341 | 4 | 4 | 28 | 0 | 224 | 242 |
| Saquon Barkley | NYG | 3 | 53 | 317 | 2 | 13 | 91 | 0 | 200 | 216 |
| James Robinson | JAX | 3 | 51 | 230 | 3 | 6 | 33 | 1 | 184 | 199 |
| Khalil Herbert | CHI | 3 | 33 | 240 | 3 | 4 | 13 | 0 | 160 | 173 |
| Aaron Jones | GB | 3 | 32 | 217 | 1 | 9 | 76 | 1 | 156 | 169 |
| Clyde Edwards-Helaire | KC | 3 | 22 | 116 | 1 | 12 | 115 | 2 | 152 | 164 |
| Cordarrelle Patterson | ATL | 3 | 49 | 302 | 2 | 4 | 28 | 0 | 172 | 157 |
| Jonathan Taylor | IND | 3 | 61 | 286 | 1 | 8 | 43 | 0 | 148 | 148 |
| D'Andre Swift | DET | 3 | 27 | 231 | 1 | 8 | 77 | 1 | 160 | 146 |
| Jamaal Williams | DET | 3 | 43 | 168 | 4 | 4 | 29 | 0 | 156 | 142 |
| Miles Sanders | PHI | 3 | 42 | 216 | 1 | 6 | 13 | 0 | 108 | 132 |
| Kareem Hunt | CLE | 3 | 36 | 151 | 1 | 9 | 54 | 1 | 120 | 130 |
| Christian McCaffrey | CAR | 3 | 50 | 243 | 1 | 10 | 57 | 0 | 140 | 128 |
| Derrick Henry | TEN | 3 | 54 | 192 | 2 | 5 | 58 | 0 | 140 | 128 |
| Dalvin Cook | MIN | 3 | 43 | 203 | 1 | 7 | 37 | 0 | 116 | 125 |
| Leonard Fournette | TB | 3 | 57 | 227 | 0 | 9 | 54 | 0 | 112 | 121 |
| Tony Pollard | DAL | 3 | 28 | 156 | 1 | 6 | 69 | 0 | 108 | 117 |
| Antonio Gibson | WAS | 3 | 40 | 124 | 2 | 10 | 87 | 0 | 124 | 113 |
| Chase Edmonds | MIA | 3 | 23 | 79 | 2 | 6 | 54 | 0 | 92 | 113 |
| Javonte Williams | DEN | 3 | 37 | 176 | 0 | 15 | 77 | 0 | 100 | 108 |
| Damien Harris | NE | 3 | 35 | 160 | 2 | 6 | 31 | 0 | 116 | 106 |
| AJ Dillon | GB | 3 | 40 | 138 | 1 | 8 | 58 | 0 | 96 | 104 |
| Najee Harris | PIT | 3 | 40 | 128 | 1 | 10 | 48 | 1 | 108 | 99 |
| Melvin Gordon | DEN | 3 | 34 | 131 | 1 | 8 | 49 | 0 | 92 | 99 |
| Breece Hall * | NYJ | 3 | 21 | 112 | 0 | 13 | 101 | 1 | 104 | 95 |
| Devin Singletary | BUF | 3 | 23 | 80 | 0 | 13 | 94 | 1 | 88 | 95 |
| Joe Mixon | CIN | 3 | 58 | 163 | 0 | 13 | 103 | 0 | 104 | 95 |
| Ezekiel Elliott | DAL | 3 | 40 | 178 | 1 | 3 | -5 | 0 | 88 | 95 |
| Dameon Pierce * | HOU | 3 | 46 | 182 | 1 | 4 | 35 | 0 | 104 | 85 |
| Jeff Wilson | SF | 3 | 39 | 181 | 0 | 7 | 58 | 0 | 92 | 84 |
| David Montgomery | CHI | 3 | 35 | 159 | 0 | 5 | 38 | 0 | 76 | 82 |
| Travis Etienne * | JAX | 3 | 26 | 112 | 0 | 8 | 81 | 0 | 76 | 82 |
| Rhamondre Stevenson | NE | 3 | 29 | 145 | 1 | 7 | 34 | 0 | 88 | 80 |
