| PlayerName | Team | G | RushAtt | RushYds | RushTD | Receptions | RecYds | RecTD | FumL | MVP Score |
| Adrian Peterson | MIN | 8 | 167 | 798 | 9 | 16 | 125 | 1 | 0 | 568 |
| LeSean McCoy | PHI | 7 | 135 | 754 | 8 | 23 | 138 | 2 | 0 | 556 |
| Fred Jackson | BUF | 7 | 132 | 721 | 6 | 27 | 353 | 0 | 0 | 548 |
| Matt Forte | CHI | 7 | 124 | 672 | 2 | 38 | 419 | 1 | 0 | 496 |
| Ray Rice | BAL | 7 | 115 | 489 | 5 | 33 | 373 | 2 | 1 | 464 |
| Arian Foster | HOU | 6 | 135 | 532 | 4 | 22 | 317 | 1 | 0 | 436 |
| Michael Turner | ATL | 7 | 138 | 621 | 6 | 7 | 98 | 0 | 1 | 384 |
| Darren McFadden | OAK | 7 | 113 | 614 | 4 | 19 | 154 | 1 | 1 | 384 |
| Ryan Mathews | SD | 7 | 111 | 509 | 3 | 30 | 342 | 0 | 1 | 380 |
| Maurice Jones-Drew | JAC | 8 | 166 | 740 | 3 | 12 | 85 | 0 | 1 | 368 |
| Ahmad Bradshaw | NYG | 7 | 111 | 440 | 5 | 24 | 210 | 1 | 1 | 360 |
| Darren Sproles | NO | 8 | 45 | 305 | 2 | 51 | 389 | 2 | 0 | 356 |
| Frank Gore | SF | 7 | 140 | 675 | 5 | 12 | 71 | 0 | 2 | 356 |
| Beanie Wells | ARI | 6 | 113 | 506 | 7 | 4 | 12 | 0 | 0 | 344 |
| Jahvid Best | DET | 6 | 84 | 390 | 2 | 27 | 287 | 1 | 0 | 328 |
| Steven Jackson | STL | 6 | 84 | 449 | 4 | 16 | 83 | 1 | 0 | 312 |
| BenJarvus Green-Ellis | NE | 7 | 96 | 400 | 5 | 4 | 38 | 0 | 0 | 272 |
| Jonathan Stewart | CAR | 8 | 71 | 327 | 2 | 23 | 220 | 0 | 0 | 256 |
| Shonn Greene | NYJ | 7 | 113 | 426 | 2 | 14 | 77 | 0 | 0 | 240 |
| Mike Tolbert | SD | 6 | 47 | 163 | 3 | 28 | 231 | 2 | 1 | 236 |
| Cedric Benson | CIN | 6 | 117 | 458 | 2 | 5 | 24 | 0 | 0 | 232 |
| Rashard Mendenhall | PIT | 7 | 107 | 421 | 3 | 9 | 48 | 0 | 1 | 224 |
| Willis McGahee | DEN | 6 | 103 | 460 | 1 | 11 | 49 | 1 | 1 | 220 |
| LeGarrette Blount | TB | 5 | 77 | 328 | 3 | 4 | 58 | 0 | 0 | 212 |
| Pierre Thomas | NO | 8 | 58 | 245 | 1 | 24 | 217 | 1 | 1 | 204 |
| Chris Johnson | TEN | 7 | 107 | 302 | 1 | 27 | 160 | 0 | 0 | 204 |
| James Starks | GB | 7 | 83 | 374 | 1 | 18 | 137 | 0 | 1 | 204 |
| Ben Tate | HOU | 7 | 97 | 508 | 1 | 5 | 40 | 0 | 2 | 196 |
| Tim Hightower | WAS | 5 | 84 | 321 | 1 | 10 | 78 | 1 | 0 | 196 |
| Michael Bush | OAK | 7 | 60 | 237 | 3 | 9 | 111 | 0 | 0 | 196 |
| DeMarco Murray | DAL | 7 | 58 | 400 | 1 | 5 | 21 | 0 | 0 | 188 |
| DeAngelo Williams | CAR | 8 | 75 | 363 | 1 | 10 | 61 | 0 | 0 | 188 |
| PlayerName | Pos | Team | G | Receptions | RecYds | RecTD | FumL | MVP Score |
| Calvin Johnson | WR | DET | 8 | 47 | 804 | 11 | 0 | 760 |
| Wes Welker | WR | NE | 7 | 57 | 824 | 6 | 0 | 568 |
| Mike Wallace | WR | PIT | 8 | 43 | 800 | 5 | 0 | 520 |
| Steve Smith | WR | CAR | 8 | 46 | 918 | 4 | 1 | 484 |
| Jimmy Graham | TE | NO | 8 | 49 | 713 | 5 | 0 | 484 |
| Greg Jennings | WR | GB | 7 | 42 | 677 | 5 | 0 | 468 |
| A.J. Green | WR | CIN | 7 | 33 | 516 | 5 | 0 | 404 |
| Rob Gronkowski | TE | NE | 7 | 36 | 495 | 5 | 0 | 396 |
| Dwayne Bowe | WR | KC | 7 | 33 | 558 | 4 | 0 | 380 |
| Hakeem Nicks | WR | NYG | 7 | 38 | 575 | 3 | 0 | 348 |
| Jordy Nelson | WR | GB | 7 | 24 | 465 | 4 | 0 | 344 |
| Pierre Garcon | WR | IND | 8 | 37 | 569 | 4 | 1 | 344 |
| Jeremy Maclin | WR | PHI | 7 | 40 | 543 | 4 | 1 | 336 |
| Stevie Johnson | WR | BUF | 7 | 39 | 439 | 4 | 0 | 332 |
| Larry Fitzgerald | WR | ARI | 7 | 34 | 603 | 2 | 0 | 320 |
| Victor Cruz | WR | NYG | 7 | 28 | 497 | 4 | 1 | 316 |
| Tony Gonzalez | TE | ATL | 7 | 35 | 380 | 4 | 0 | 312 |
| Jason Witten | TE | DAL | 7 | 40 | 477 | 3 | 0 | 308 |
| Vincent Jackson | WR | SD | 7 | 27 | 472 | 3 | 0 | 308 |
| Dez Bryant | WR | DAL | 6 | 22 | 367 | 4 | 0 | 304 |
| Greg Olsen | TE | CAR | 8 | 30 | 359 | 4 | 0 | 300 |
| Eric Decker | WR | DEN | 7 | 30 | 359 | 5 | 1 | 300 |
| Miles Austin | WR | DAL | 5 | 26 | 350 | 4 | 0 | 300 |
| Plaxico Burress | WR | NYJ | 7 | 18 | 243 | 5 | 0 | 296 |
| Jermichael Finley | TE | GB | 7 | 25 | 334 | 4 | 0 | 292 |
| Anquan Boldin | WR | BAL | 7 | 34 | 539 | 2 | 0 | 292 |
| Scott Chandler | TE | BUF | 7 | 15 | 133 | 6 | 0 | 292 |
| Roddy White | WR | ATL | 7 | 39 | 425 | 3 | 0 | 288 |
| Owen Daniels | TE | HOU | 8 | 31 | 415 | 3 | 0 | 284 |
| Fred Davis | TE | WAS | 7 | 36 | 517 | 2 | 0 | 284 |
| Deion Branch | WR | NE | 7 | 30 | 405 | 3 | 0 | 280 |
| DeSean Jackson | WR | PHI | 7 | 27 | 487 | 2 | 0 | 272 |
| PlayerName | Pos | Team | G | Tack | Sack | Ints | FFum | PD | MVP Score |
| Jared Allen | DE | MIN | 8 | 34 | 13 | 1 | 3 | 4 | 734 |
| DeMarcus Ware | LB | DAL | 7 | 31 | 12 | 0 | 2 | 1 | 571 |
| Jason Pierre-Paul | DE | NYG | 7 | 35 | 9 | 0 | 1 | 4 | 495 |
| Brandon Flowers | CB | KC | 7 | 31 | 0 | 4 | 0 | 15 | 491 |
| LaMarr Woodley | LB | PIT | 8 | 36 | 9 | 1 | 0 | 2 | 476 |
| Jason Babin | DE | PHI | 7 | 22 | 9 | 0 | 1 | 1 | 422 |
| Terrell Suggs | LB | BAL | 7 | 33 | 6 | 1 | 2 | 3 | 413 |
| Charles Woodson | CB | GB | 7 | 26 | 1 | 5 | 0 | 7 | 406 |
| Chris Houston | CB | DET | 8 | 41 | 0 | 4 | 0 | 10 | 401 |
| Darrelle Revis | CB | NYJ | 7 | 20 | 0 | 4 | 0 | 10 | 380 |
| Aldon Smith | LB | SF | 7 | 13 | 7 | 0 | 1 | 3 | 373 |
| George Wilson | S | BUF | 7 | 66 | 0 | 4 | 1 | 6 | 366 |
| Eric Weddle | S | SD | 7 | 41 | 0 | 5 | 0 | 6 | 361 |
| Morgan Burnett | S | GB | 7 | 49 | 1 | 3 | 2 | 5 | 349 |
| Charles Johnson | DE | CAR | 8 | 28 | 7 | 0 | 1 | 1 | 348 |
| Johnathan Joseph | CB | HOU | 8 | 26 | 0 | 3 | 1 | 9 | 346 |
| Von Miller | LB | DEN | 7 | 26 | 6 | 0 | 2 | 2 | 346 |
| Lardarius Webb | CB | BAL | 7 | 38 | 1 | 2 | 1 | 8 | 338 |
| Corey Webster | CB | NYG | 7 | 26 | 0 | 3 | 0 | 9 | 326 |
| Kam Chancellor | S | SEA | 6 | 45 | 1 | 3 | 0 | 6 | 325 |
| Kyle Arrington | CB | NE | 7 | 40 | 0 | 4 | 0 | 6 | 320 |
| Carlos Rogers | CB | SF | 7 | 19 | 0 | 3 | 0 | 9 | 319 |
| Jason McCourty | CB | TEN | 7 | 59 | 1 | 2 | 1 | 6 | 319 |
| Cliff Avril | DE | DET | 8 | 17 | 5 | 0 | 3 | 2 | 317 |
| Ray Lewis | LB | BAL | 7 | 55 | 2 | 1 | 2 | 5 | 315 |
| Jabari Greer | CB | NO | 8 | 32 | 0 | 1 | 0 | 12 | 312 |
| Roman Harper | S | NO | 8 | 47 | 5 | 0 | 1 | 2 | 307 |
| Brian Orakpo | LB | WAS | 7 | 27 | 5 | 0 | 2 | 2 | 307 |
| Aaron Ross | CB | NYG | 7 | 24 | 0 | 3 | 0 | 8 | 304 |
| London Fletcher | LB | WAS | 7 | 63 | 1 | 2 | 1 | 5 | 303 |
| Daryl Smith | LB | JAC | 8 | 57 | 2 | 1 | 1 | 5 | 297 |
| Chris Long | DE | STL | 7 | 14 | 6 | 0 | 0 | 2 | 294 |
